产品货号:
Z19327
中文名称:
KPNA4抗体
英文名称:
Anti-KPNA4 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-KPNA4 Antibody |
指标别名 | Importin alpha Q1;Importin subunit alpha 4;IPOA3;Karyopherin subunit alpha 4;KPNA4;QIP1;SRP3 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,ICC,IF |
基因名称 | KPNA4 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | KPNA4 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human KPNA4.The immunogen is located within amino acids 30 - 80 of KPNA4. |
计算分子量 | 58kDa |
成分 | KPNA4 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | KPNA4 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Karyopherin,a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits,is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring,Ran-dependent mechanism.The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm,while the beta subunit accumulates at the NPC.Molecules containing the classical nuclear localization signal (NLS) are transported into the nucleus by alpha/beta heterodimers.KPNA3 has been shown to be important in the TNF-汐-induced nuclear import of NF-百B.It is also involved in the stress-mediated nuclear stabilization of p53 and the nuclear import and replication of HIV-1 in both dividing and non-dividing cells. |
Uniprot ID | O00629 |
基因名全称 | Karyopherin alpha 4 (importin alpha 3) |
蛋白名全称 | Karyopherin alpha 4 (importin alpha 3) |
推荐稀释比 | KPNA4 antibody can be used for detection of KPNA4 by Western blot at 1μg/mL.Antibody can also be used for immunocytochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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